Anti-MLXIPL Rabbit Polyclonal Antibody

Supplier: Proteintech
10090-288EA 402 USD
Anti-MLXIPL Rabbit Polyclonal Antibody
Carbohydrate response element-binding protein (ChREBP), also known as MLXIPL, is a glucose-responsive transcription factor that has a fundamental role in the glucose-mediated induction of genes involved in hepatic glycolysis and lipogenesis. Circulating blood glucose levels affect ChREBP activity in hepatocytes largely by post-translational mechanisms that include phosphorylation-dependent subcellular localization . It enhances expression of the liver pyruvate kinase (LPK) gene and all lipogenic enzyme genes resulting in the conversion of excess dietary carbohydrate into triglycerides that can be stored as fat . Molecular Weight of ChREBP splice variants: 62/78/91/93 kDa.

Western Blot: HepG2 Cells, 1:500-1:5000

Type: Primary
Antigen: MLXIPL
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human
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