Anti-STAT5A Rabbit Polyclonal Antibody

Supplier: Proteintech

Anti-STAT5A Rabbit Polyclonal Antibody

Anti-STAT5A Rabbit Polyclonal Antibody

Anti-STAT5A Rabbit Polyclonal Antibody

Anti-STAT5A Rabbit Polyclonal Antibody

Anti-STAT5A Rabbit Polyclonal Antibody

Anti-STAT5A Rabbit Polyclonal Antibody

13179-1-AP-150UL

10095-266EA 402 USD

10095-266

Anti-STAT5A Rabbit Polyclonal Antibody

Antibodies

STAT5A, also named as STAT5, belongs to the transcription factor STAT family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. STAT5A is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of STAT5A in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for the tumorigenesis. The mouse counterpart of human STAT5A is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of STAT5A in cells. This antibody is a rabbit polyclonal antibody raised against residues near the C terminus of human STAT5A.

Western Blot:K-562 Cells, 1:500-1:5000; IHC: Human breast cancer Tissue, 1:20-1:200; FC: MCF-7 Cells, N/A

Type: Primary
Antigen: STAT5A
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat

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