QKI belongs to a family of RNA-binding proteins, which have an HNRNPK homology (KH) domain embedded in a 200-amino acid region called the GSG domain. It involves in regulation of RNA splicing, export of target RNAs from the nucleus, translation of proteins, and RNA stability. Also it required to protect and promote stability of mRNAs such as MBP and CDKN1B. Beside, it acts as a regulator of oligodendrocyte differentiation and maturation in the brain that may play a role in myelin and oligodendrocyte dysfunction in schizophrenia.
Western Blot:K-562 Cells, 1:500-1:5000
Type: Primary
Antigen: QKI
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat