Anti-CTNS Rabbit Polyclonal Antibody

Supplier: Proteintech
10085-320EA 402 USD
Anti-CTNS Rabbit Polyclonal Antibody
The CTNS or cystinosin is a lysosomal membrane protein which comprises with seven transmembrane domains, a 128 amino acid N-terminal region bearing seven N-glycosylation sites and a cytosolic C-terminal GYDQL sorting motif. It functions as a H+-driven cystine transporter responsible for cystine export from lysosomes. The mutation of CTNS gene cause an inherited disorder, cystinosis, characterized by defective lysosomal efflux of cystine. This antibody was raised against the N-terminal region of human cystinosin. Two isoforms of CTNS exist due to alternative splicing events and both of them can be detected through this antibody.

Western Blot: HEK-293 Cells, 1:200-1:2000; IHC: Human pancreas cancer, 1:20-1:200

Type: Primary
Antigen: CTNS
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
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