Anti-PGRMC1 Rabbit Polyclonal Antibody

Supplier: Proteintech
10092-164EA 402 USD
Anti-PGRMC1 Rabbit Polyclonal Antibody
Progesterone receptor membrane component 1 (PGRMC1) is a member of a multi-protein progesterone-binding complex. However, PGRMC1 shares homology with cytochrome b5-related proteins rather than hormone receptors . It is a heme binding protein with biding sites for Src homology (SH2) and SH3 domain-containing proteins . PGRMC1 is overexpressed in a variety of cancers, and thus represents an important biomarker for cancer progression and a potential target for anticancer drugs . In nonmalignant tissues, PGRMC1 is highly expressed in the liver and kidney .

Western Blot: HEK-293 Cells, 1:500-1:5000; IHC: Human cervical cancer Tissue, 1:20-1:200; IP: MCF-7 Cells, 1:500-1:5000

Type: Primary
Antigen: PGRMC1
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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