IMPDH2, also named as IMPD2, belongs to the IMPDH/GMPR family. It is a rate limiting enzyme in the de novo synthesis of guanine nucleotides and therefore is involved in the regulation of cell growth. It may also have a role in the development of malignancy and the growth progression of some tumors. IMPDH2 is a key enzyme in the purine nucleotide biosynthetic pathway and constitutes a pivotal biological target for immunosuppressant and antiviral drugs. IMPDH2 is highly enriched in RR(filamentous rods and rings).
Western Blot: Human Heart Tissue, 1:500-1:5000; IHC: Human lung cancer Tissue, 1:20-1:200; IF: Hela Cells, 1:10-1:100; IP:K-562 Cells, 1:200-1:2000
Type: Primary
Antigen: IMPDH2
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat