Anti-PSME2 Rabbit Polyclonal Antibody

Supplier: Proteintech

Anti-PSME2 Rabbit Polyclonal Antibody

Anti-PSME2 Rabbit Polyclonal Antibody

Anti-PSME2 Rabbit Polyclonal Antibody

Anti-PSME2 Rabbit Polyclonal Antibody

12937-2-AP-150UL

10092-990EA 402 USD

10092-990

Anti-PSME2 Rabbit Polyclonal Antibody

Antibodies

The principal function of the proteasome is targeted degradation of intracellular proteins. Activity of the 20S proteasome is controlled by regulatory complexes that bind to the ends of the cylindrical proteasome. 11S regulator (REG or PA28), is a complex of 28 kDa subunits that is thought to activate proteasomes toward the production of antigenic peptides. Human PSME1 and PSME2 genes encode the two proteasome activators PA28 alpha and beta, respectively, which have been implicated in antigen processing for loading class I MHC molecules. The PA28 activator complex enhances the generation of class I binding peptides by altering the cleavage pattern of the proteasome.

Western Blot: HepG2 Cells, 1:500-1:5000; IP: MCF-7 Cells, 1:200-1:2000

Type: Primary
Antigen: PSME2
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat

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