Anti-HDAC2 Rabbit Polyclonal Antibody

Supplier: Proteintech
12922-3-AP-150UL
10088-124EA 402 USD
10088-124
Anti-HDAC2 Rabbit Polyclonal Antibody
Antibodies
Histone deacetylases(HDAC) are a class of enzymes that remove the acetyl groups from the lysine residues leading to the formation of a condensed and transcriptionally silenced chromatin.Histone deacetylases act via the formation of large multiprotein complexes, and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4). At least 4 classes of HDAC were identified. As a class I HDAC, HDAC2 was primarily found in the nucleus. HDAC2 forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events. This antibody is a rabbit polyclonal antibody raised against residues near the C terminus of human HDAC2.

Western Blot: HEK-293 Cells, 1:500-1:5000; IHC: Human Prostate Cancer Tissue, 1:20-1:200; IF: HepG2 Cells, 1:10-1:100; IP: Mouse Testis Tissue, 1:500-1:5000; FC: HEK-293T Cells, N/A

Type: Primary
Antigen: HDAC2
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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