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Anti-SRRM1 Rabbit Polyclonal Antibody

Supplier: Proteintech
SRRM1, also named as SRM160 and POP101, contains one PWI domain and belongs to the splicing factor SR family. As part of pre- and post-splicing multiprotein mRNP complexes, SRRM1 is involved in numerous pre-mRNA processing events. It promotes constitutive and exonic splicing enhancer (ESE)-dependent splicing activation by bridging together sequence-specific (SR family proteins, SFRS4, SFRS5 and TRA2B/SFRS10) and basal snRNP (SNRP70 and SNRPA1) factors of the spliceosome. SRRM1 stimulates mRNA 3'-end cleavage independently of the formation of an exon junction complex. It binds both pre-mRNA and spliced mRNA 20-25 nt upstream of exon-exon junctions. SRRM1 binds RNA and DNA with low sequence specificity and has similar preference for either double- or single-stranded nucleic acid substrates. SRRM1, a protein of high molecular weight(120-160kd), has a heavy glycosylation level and is normally highly phosphorylated. This antibody is a rabbit polyclonal antibody raised against residues near the N terminus of human SRRM1.

Western Blot: Mouse Liver Tissue, 1:200-1:2000

Type: Primary
Antigen: SRRM1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat



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Size Supplier No. VWR Catalog Number Unit Price Quantity
150 µL 12822-1-AP 10095-192 Each (150µl) Retrieving Restricted

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SPECIFICATIONS

Antigen Symbol SRRM1
Antigen Name Serine/Arginine Repetitive Matrix 1
Reactivity Rat, Human, Mouse
Conjugation Unconjugated
Clonality Polyclonal
Antibody Type Primary
Host Rabbit
Isotype IgG
Western Blot Yes
ELISA Yes
Antigen Synonyms Ser/Arg related nuclear matrix protein, SR-related nuclear matrix protein of 160 kDa, SR related nuclear matrix protein of 160 kDa, Ser/Arg-related nuclear matrix protein, SRm160, Serine/arginine repetitive matrix protein 1, Srrm1, SRRM1_HUMAN.
Immunogen Recombinant Protein
Purification Antigen affinity Purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Shipping Temperature Store at -20°C
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