BCL2 belongs to the Bcl-2 family. It is a suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. BCL2 regulates cell death by controlling the mitochondrial membrane permeability . It appears to function in a feedback loop system with caspases. BCL2 inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1) .
Western Blot: HL-60 Cells, 1:500-1:5000; IHC: Human tonsillitis Tissue, 1:20-1:200; IP: MCF-7 Cells, 1:500-1:5000
Type: Primary
Antigen: BCL2
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human