Anti-IFITM2 Rabbit Polyclonal Antibody

Supplier: Proteintech
10081-554EA 537.7 USD
Anti-IFITM2 Rabbit Polyclonal Antibody
IFITM2, also named as 1-8D, belongs to the CD225 family. It is an IFN-induced antiviral protein that mediates cellular innate immunity to at least three major human pathogens, namely influenza A H1N1 virus, West Nile virus (WNV), and dengue virus , by inhibiting the early steps of replication. IFITM2 induces cell cycle arrest and mediates apoptosis by caspase activation and in p53-independent manner. It is overexpressed in colon carcinoma. IFITM2 is a novel pro-apoptotic gene that will provide new insights into the regulated cellular pathways to death. IFITM proteins are recently identified as viral restriction factors that inhibit infection mediated by the influenza A virus (IAV) hemagglutinin (HA) protein. Also they serve as important components of the innate immune system to restrict HIV-1 infection. Catalog#12769-1-AP is a rabbit polyclonal antibody produced with full-length of human IFITM2.

IHC: Human breast cancer Tissue, 1:20-1:200; IP: HepG2 Cells, 1:200-1:1000; Western Blot: MCF7 Cells, 1:200-1:2000; IF: HepG2 Cells, 1:20-1:200

Type: Primary
Antigen: IFITM2
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human
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