Anti-ZNF238 Rabbit Polyclonal Antibody

Supplier: Proteintech
10097-320EA 402 USD
Anti-ZNF238 Rabbit Polyclonal Antibody
ZNF238 is a member of the BTB/POZ-ZF protein family, which involve in development and cancer formation, for example BCL-6, PLZF, and HIC-1. It's a transcriptional repressor involve in myogenesis and brain development. By directly repressing the expression of two skeletal myogenesis inhibitors, ID2 and ID3, ZNF238 plays a key role in myogenesis. It can control cell division of progenitor cells and regulating the survival of postmitotic cortical neurons. Besides, ZNF238 involves in the organization of nuclear chromosomes, for its specific binding to the consensus DNA sequence that contains the E box core, and recruiting chromatin remodeling multiportein complex. ZNF238 proteins has apparent molecular masses of 60 and 48 kD. Specific binding is found for a 60-kDa band which corresponds to the full length of RP58 protein. In addition, a 48-kDa band, thought to be the truncated form 2 is detected .

Western Blot: Mouse Brain Tissue, 1:500-1:5000; IP: Mouse cerebellum Tissue, 1:500-1:5000; IHC: Mouse Brain Tissue, 1:20-1:200

Type: Primary
Antigen: ZNF238
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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