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Anti-GCNF Rabbit Polyclonal Antibody

Supplier: Proteintech
NR6A1 (Nuclear Receptor Subfamily 6 Group A member), also known as GCNF (Germ Cell Nuclear Factor), is an orphan member of the nuclear receptor gene superfamily. It has been shown to be expressed in the nervous system during development and during specific stages in maturing germ cells of the ovary and testis in the adult, and has probable roles in gametogenesis, neurogenesis, and normal embryonic development during gastrulation. Inactivation of GCNF in mouse results in abnormal posterior development, impaired midbrain development, insufficient closure of the neural tube, and eventual embryonic death. GCNF has been shown to be a repressor of OCT-4 and of the protamine genes and plays a critical role in the control of gene expression during embryogenesis and spermatogenesis. This antibody specifically reacts with the 55kd NR6A1 protein.

Western Blot:PC-3 Cells, 1:500-1:5000; IHC: Human Testis Tissue, 1:20-1:200

Type: Primary
Antigen: GCNF
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat



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Size Supplier No. VWR Catalog Number Unit Price Quantity
150 µL 12712-1-AP 10087-446 Each (150µl) Retrieving Restricted

Temperature sensitive This Item is temperature-controlled and may have specific temperature and storage requirements for shipping/delivery.

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Antigen Symbol GCNF
Antigen Name Germ Cell Nuclear Factor
Reactivity Rat, Mouse, Human
Conjugation Unconjugated
Clonality Polyclonal
Antibody Type Primary
Host Rabbit
Isotype IgG
Western Blot Yes
ImmunoChemistry Yes
Antigen Synonyms Retinoid receptor related testis specic receptor, Retinoid receptor-related testis-specic receptor, GCNF, Nuclear receptor subfamily 6 group A member 1, NR 61, RTR., NR6A1_HUMAN, NR6A1, GCNF 1, Germ cell nuclear factor, hRTR, NR61, GCNF1, Orphan nuclear receptor NR6A1, hGCNF, Retinoic acid receptor related testis associated receptor
Immunogen Recombinant Protein
Purification Antigen affinity Purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Shipping Temperature Store at -20°C
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