FAK (Focal adhesion kinase 1) is also named as FAK1, FADK, pp125FAK, FAK and belongs to the protein kinase superfamily. It is a critical tyrosine kinase that modulates cell adhesion, migration, proliferation and survival in response to extracellular signals . It also acts as a pivotal signal 'integrator', controlling and coordinating cellular responses that include cell migration, survival, proliferation and, epithelial tissue repair after DNA damage . This protein has 6 isoforms produced by alternative promoter usage and alternative splicing.
Western Blot: MCF7 Cells, 1:500-1:5000; IHC: Human gliomas Tissue, 1:20-1:200; IP: Mouse Brain Tissue, 1:1000-1:10000
Type: Primary
Antigen: FAK
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat