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Anti-CDH13 Rabbit Polyclonal Antibody

Supplier: Proteintech

Cadherins are a family of transmembrane glycoproteins that mediate calcium-dependent cell-cell adhesion and play an important role in the maintenance of normal tissue architecture. Cadherin-13 (CDH13, also known as H-cadherin or T-cadherin) is an atypical member of cadherin family, lacking transmembrane and cytosolic domains and anchored to the exterior surface of the plasma membrane via a GPI anchor. CDH13 is thought to affect cellular behavior largely through its signaling properties. It is highly expressed in heart, and in the CNS, CDH13 is expressed in cerebral cortex, medulla, hippocampus, amygdala, thalamus and substantia nigra. It is often down-regulated in cancerous cells. The CDH13 cDNA encodes a 713-amino acid protein, which has a calculated molecular weight of 78 kDa. Studies have detected variable bands on Western blots, including 105 kDa (mature form), 130 kDa (precursor), and 45 kDa, which may be a post-translational processing variant of CDH13 .

Western Blot: Mouse Heart Tissue, 1:200-1:2000; IHC: Human endometrial cancer Tissue, 1:20-1:200; FC:Jurkat Cells, N/A

Type: Primary
Antigen: CDH13
Clonality: Polyclonal
Clone: 0
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG

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Size Supplier No. VWR Catalog Number Unit Price Quantity
150 µL 12618-1-AP 10083-948 Each (150µl) Retrieving Restricted
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Antibody Type Primary
Antigen Name Cadherin 13
Antigen Symbol CDH13
Antigen Synonyms CDH13, Truncated Cadherin, P105, Cadherin-13, T-Cadherin, T-cad, CDHH, H-Cadherin, Heart Cadherin
Clonality Polyclonal
Conjugation Unconjugated
Flow Cytometry Yes
Host Rabbit
ImmunoChemistry Yes
Immunogen Recombinant Protein
Isotype IgG
Purification Antigen affinity Purification
Reactivity Mouse, Human
Shipping Temperature Store at -20°C
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Western Blot Yes
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