Human SCO1 and SCO2 are metallochaperones that are essential for the assembly of the catalytic core of cytochrome c oxidase (COX). SCO1 appears to be involved in the folding and assembly of cytochrome oxidase subunit II, and possibly of other proteins of this subcompartment. It is a 33 kDa protein which displays limited homology to members of the DnaJ family. It is also named as SCOD1 and belongs to the SCO1/2 family. It can exsit as a homodimer. Defects in SCO1 are a cause of mitochondrial complex IV deficiency (MT-C4D).
Western Blot: Human Heart Tissue, 1:200-1:2000
Type: Primary
Antigen: SCO1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human