UNG(Uracil-DNA glycosylase) removes uracil in DNA resulting from deamination of cytosine or replicative incorporation of dUMP instead of dTMP. Thus, UNG plays a role in suppressing GC-to-AT transition mutations.The UNG gene encodes 2 isoforms that are individually targeted to the mitochondria and the nucleus.Defects in UNG are a cause of immunodeficiency with hyper-IgM type 5 (HIGM5).
Western Blot: Human Testis Tissue, 1:200-1:2000; IHC: Human Testis Tissue, 1:20-1:200
Type: Primary
Antigen: UNG
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat