Anti-CA8 Rabbit Polyclonal Antibody

Supplier: Proteintech
10083-924EA 402 USD
Anti-CA8 Rabbit Polyclonal Antibody
The CA8 (CARP) gene encodes carbonic anhydrase VIII, which is part of a family of zinc metalloenzyme. CA8 has a central carbonic anhydrase motif, but it lacks carbonic anhydrase activity due to absence of catalytic zinc coordinating residues. CARP is a novel IP3R1-binding protein, and is expressed in Purkinje cells abundantly. CA8 is co-localized with IP3R1 in Purkinje cells and it binds to IP3R1, reducing the affinity of the receptor for its ligand, IP3. Defects in CA8 are the cause of cerebellar ataxia mental retardation and dysequilibrium syndrome type 3 (CMARQ3).

Western Blot: Mouse Skeletal Muscle Tissue, 1:200-1:2000; IHC: Human gliomas Tissue, 1:20-1:200

Type: Primary
Antigen: CA8
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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