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Anti-LIMK2 Rabbit Polyclonal Antibody

Supplier: Proteintech

The family of LIM kinase (LIMK) includes two similar proteins, LIMK1 and LIMK2, that share overall identity of 53% with 75%, 55%, and 42% amino acid identity in the LIM, kinase, and PDZ domains, respectively. LIMK2 regulates actin cytoskeletal reorganization through phosphorylating and inactivating cofilin, an actin-depolymerizing factor of actin filaments. It also may associate with gamma-tubulin and play a role in mitotic spindle assembly. High levels of LIMK2 are evident in uterus, thymus, and spleen whereas lower levels are observed in brain, heart, liver, stomach, skeletal muscle, and testes according to the results of western blotting. It has 3 isoforms produced by alternative splicing of the molecular weight of 70-78 kDa. It can be detected a band of 47 kDa or 50-55 kDa in the testes because the antibody is recognizing the testis-specific variant of LIMK2 and the this difference could be due to species variation.

Type: Primary
Antigen: LIMK2
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat




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Size Supplier No. VWR Catalog Number Unit Price Quantity
150 µL 12350-1-AP 10089-630 Each (150µl) Retrieving Restricted
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SPECIFICATIONS

Antibody Type Primary
Antigen Name LIM Domain kinase 2
Antigen Symbol LIMK2
Antigen Synonyms LIMK2, LIMK, LIM domain kinase 2, LIMK 2
Clonality Polyclonal
Conjugation Unconjugated
ELISA Yes
Host Rabbit
Immunogen Recombinant Protein
Isotype IgG
Purification Antigen affinity Purification
Reactivity Mouse, Human, Rat
Shipping Temperature Store at -20°C
Storage Buffer PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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