Anti-MAGOH Rabbit Polyclonal Antibody

Supplier: Proteintech

Anti-MAGOH Rabbit Polyclonal Antibody

Anti-MAGOH Rabbit Polyclonal Antibody

Anti-MAGOH Rabbit Polyclonal Antibody

Anti-MAGOH Rabbit Polyclonal Antibody

12347-1-AP-150UL

10089-906EA 402 USD

10089-906

Anti-MAGOH Rabbit Polyclonal Antibody

Antibodies

MAGOH, belonging to the mago nashi family, is a component of a splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of a few core proteins and several more peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Core components of the EJC functions to mark the position of the exon-exon junction in the mature mRNA and thereby influences downstream processes of gene expression including mRNA splicing, nuclear mRNA export, subcellular mRNA localization, translation efficiency and nonsense-mediated mRNA decay (NMD). MAGOH regulates the transcriptional activation of STAT3 by interfering complex formation between STAT3 and a core EJC component Y14.

Western Blot: Human Brain Tissue, 1:200-1:2000; IHC: Human ovary tumor Tissue, 1:20-1:200; IP:K-562 Cells, 1:200-1:2000

Type: Primary
Antigen: MAGOH
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human

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