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Anti-CRB3 Rabbit Polyclonal Antibody

Supplier: Proteintech

Crumbs is an apical transmembrane protein crucial for epithelial morphogenesis in Drosophila melanogaster embryos. Three isoforms of mammalian Crumbs have been identified, and two have been characterized. Crumbs1 (CRB1) is expressed primarily in the central nervous system, whereas Crumbs3 (CRB3) is mainly expressed in epithelial tissues and skeletal muscles. CRB3 is an N-glycosylated, small transmembrane protein. CRB3 has a conserved cytoplasmic domain containing the two motives GTY and ERLI found in Crumbs, but exhibits a very short extracellular domain without the EGF- and laminin A-like G repeats present in the other Crumbs. Through its cytoplasmic domain and its interactors (e.g., Pals1 and Par6), CRB3 plays a role in apical membrane morphogenesis and tight junction regulation.

Type: Primary
Antigen: CRB3
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype:
Reactivity:



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Size Supplier No. VWR Catalog Number Unit Price Quantity
150 µL 12315-1-AP 10085-160 Each (150µl) Retrieving Restricted
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SPECIFICATIONS

Antigen Symbol CRB3
Antigen Name Crumbs Family Member 3
Reactivity Human
Conjugation Unconjugated
Clonality Polyclonal
Antibody Type Primary
Host Rabbit
Isotype IgG
ELISA Yes
Immunogen Recombinant Protein
Purification Antigen affinity Purification
Storage Buffer PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Shipping Temperature Store at -20°C
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