AGR2, also named AG2 or HPC8, encodes anterior gradient protein 2 homolog which belongs to the AGR family. It is a secreted protein localized in endoplasmic reticulum. AGR2 plays roles in MUC2 post-transcriptional synthesis,secretion and production of mucus by intestinal cells. AGR2 was significantly elevated in the pancreatic juice from patients with pre-malignant conditions as well as pancreatic cancer compared to control pancreatic juice samples. AGR2 levels in pancreatic juice could potentially be used to aide in assessment of high-risk patients undergoing endoscopic procedures.
Western Blot: Mouse Stomach Tissue, 1:1000-1:10000; IHC: Human breast cancer Tissue, 1:20-1:200; IP:SW 1990 Cells, 1:500-1:5000; FC: MCF-7 Cells, N/A; IF: MCF-7 Cells, 1:10-1:100
Type: Primary
Antigen: AGR2
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat