DYRK1B(dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B) is also named as MIRK. It is a member of the dyrk/minibrain family of serine/threonine kinases that mediate the transition from growth to differentiation in lower eukaryotes and mammals. DYRK1B functions as a transcriptional coactivator that is activated by co-expressed MKK3, a MAP kinase that also can activate p38 MAP kinase. The DYRK1B splice variants found in each muscle tissue exhibit approximate molecular weights of 70 and 75 kDa. It has 3 isoforms produced by alternative splicing of the molecular weight of 65-69 kDa.
Western Blot: Mouse Testis Tissue, 1:1000-1:10000
Type: Primary
Antigen: DYRK1B
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat