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Anti-CTSB Rabbit Polyclonal Antibody

Supplier: Proteintech
CTSB(Cathepsin B) is also named as CPSB and belongs to the peptidase C1 family. It participates in intracellular degradation and turnover of proteins. Cathepsin B precursors found in human malignant ascites fluid do not possess mannose-rich carbohydrates suggesting that a defect in the post translational processing of carbohydrate moieties on tumor cathepsin B may be responsible for the release of cathepsin B observed in many tumor systems. Cathepsin B exists as both glycosylated and unglycosylated forms. In rat macrophages and hepatocytes pro- cathepsin B is 39 kDa (unglycosylated =35 kDa), whereas in human fibroblasts procathepsin B is 44.5-46kDa (unglycosylated=39kDa). It can be detected the 43 kDa form of pro-CTSB, 31 kDa and 25 kDa marure forms in mouse brain by western blot.

Western Blot:A375 Cells, 1:200-1:2000; IHC: Human breast cancer Tissue, 1:20-1:200; IF:A375 Cells, 1:10-1:100; FC: MCF-7 Cells, N/A

Type: Primary
Antigen: CTSB
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype:
Reactivity:



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Size Supplier No. VWR Catalog Number Unit Price Quantity
150 µL 12216-1-AP 10084-100 Each (150µl) Retrieving Restricted
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SPECIFICATIONS

Antigen Symbol CTSB
Antigen Name Cathepsin B
Reactivity Human, Mouse
Conjugation Unconjugated
Clonality Polyclonal
Antibody Type Primary
Host Rabbit
Isotype IgG
Western Blot Yes
ELISA Yes
ImmunoChemistry Yes
ImmunoFluorescence Yes
Flow Cytometry Yes
Antigen Synonyms CPSB, CTSB, EC 3.4.22.1, APPS
Gene ID 1508
Immunogen Recombinant Protein
Purification Antigen affinity Purification
Storage Buffer PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Shipping Temperature Store at -20°C
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