Anti-CTSB Rabbit Polyclonal Antibody

Supplier: Proteintech
10084-100EA 402 USD
Anti-CTSB Rabbit Polyclonal Antibody
CTSB(Cathepsin B) is also named as CPSB and belongs to the peptidase C1 family. It participates in intracellular degradation and turnover of proteins. Cathepsin B precursors found in human malignant ascites fluid do not possess mannose-rich carbohydrates suggesting that a defect in the post translational processing of carbohydrate moieties on tumor cathepsin B may be responsible for the release of cathepsin B observed in many tumor systems. Cathepsin B exists as both glycosylated and unglycosylated forms. In rat macrophages and hepatocytes pro- cathepsin B is 39 kDa (unglycosylated =35 kDa), whereas in human fibroblasts procathepsin B is 44.5-46kDa (unglycosylated=39kDa). It can be detected the 43 kDa form of pro-CTSB, 31 kDa and 25 kDa marure forms in mouse brain by western blot.

Western Blot:A375 Cells, 1:200-1:2000; IHC: Human breast cancer Tissue, 1:20-1:200; IF:A375 Cells, 1:10-1:100; FC: MCF-7 Cells, N/A

Type: Primary
Antigen: CTSB
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
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