MARCH5(E3 ubiquitin-protein ligase MARCH5) is a 31 kDa protein also named as RNF153. This protein plays a protective role against mitochondrial dysfunction caused by the mitochondrial accumulation of mSOD1 via the ubiquitin-proteasome pathway. And it may regulate MAP1B LC1 function in mitochondria by controlling mitochondrial aggregation via mitochondrial LC1 levels.
Western Blot: HeLa Cells, 1:200-1:1000; IHC: Human Skeletal Muscle Tissue, 1:20-1:200; IP: HeLa Cells, 1:200-1:1000
Type: Primary
Antigen: MARCH5
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human