Anti-FBLN5 Rabbit Polyclonal Antibody

Supplier: Proteintech
10087-024EA 402 USD
Anti-FBLN5 Rabbit Polyclonal Antibody
Fibulin-5, also known as EVEC and DANCE, is a extracellular matrix glycoprotein, secreted by various cell types such as vascular smooth muscle cells, fibroblasts and endothelial cells. Structurally, Fibulin-5 contains an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. FBLN5 mutations have been described in patients with age-related macular degeneration, as well as being involved in Charcot-Marie-Tooth neuropathies. This antibody got 50kd or 66kd band in western blotting, the 66kd corresponding to fully glycosylated protein.

Western Blot: Mouse Heart Tissue, 1:200-1:2000; IHC: Human lung cancer Tissue, 1:20-1:200; IP: Mouse Heart Tissue, 1:200-1:1000

Type: Primary
Antigen: Fibulin 5
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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