Anti-UBE2C Rabbit Polyclonal Antibody

Supplier: Proteintech
10096-620EA 402 USD
Anti-UBE2C Rabbit Polyclonal Antibody
UBE2C(Ubiquitin-conjugating enzyme E2 C) is also known as UBCH10 and belongs to the ubiquitin-conjugating enzyme family. It is highly expressed in a variety of human primary tumors, and it is able to promote cell proliferation and malignant transformation. UBE2C, along with the E3 ligase of the anaphasepromoting complex (APC), catalyzes the ubiquitination of mitotic cyclins A and B, as well as securin. UBE2C is essential for cell cycle progression, and mutation of its active site cysteine confers a dominant-negative phenotype.

Western Blot: HeLa Cells, 1:200-1:2000; IHC: Human Colon cancer Tissue, 1:20-1:200

Type: Primary
Antigen: UBE2C
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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