VTCN1 also named B7H4, B7X, or B7S1 is a 282 amino acid protein, which contains 2 immunoglobulin-like domains and belongs to the immunoglobulin superfamily. VTCN1 negatively regulates T-cell mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. VTCN1 is a single-pass type I membrane protein, which is over-expressed in breast, ovarian, endometrial, renal cell and non-small-cell lung cancers. The molecular weight of VTCN1 is 31kDa, but mature VTCN1 is 50 to 80kDa glycosylated molecule with a 28kDa protein core.
Western Blot: Mouse Liver Tissue, 1:200-1:2000
Type: Primary
Antigen: VTCN1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat