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Anti-KRAS Rabbit Polyclonal Antibody

Supplier: Proteintech
KRAS, also called p21, is a member of the Ras superfamily of proteins. It is located on human chromosome 12, and contains four coding exons and a 5' non-coding exon . KRAS is a membrane-anchored guanosine triphosphate/guanosine diphosphate (GTP/GDP)-binding protein and is widely expressed in most human cells. Like other members of the Ras family, the KRAS protein is a GTPase, and it is involved in intracellular signal transduction and mainly responsible for EGFR-signaling activation . KRAS mutations have been found in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. KRAS has two isoforms, a and b. This KRAS antibody (12063-1-AP) is a Pan-RAS antibody.

Western Blot: Mouse Brain Tissue, 1:500-1:5000; IHC: Human Colon cancer Tissue, 1:20-1:200; IP: HeLa Cells, 1:500-1:5000; FC: HeLa Cells, N/A

Type: Primary
Antigen: KRAS
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat



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Size Supplier No. VWR Catalog Number Unit Price Quantity
150 µL 12063-1-AP 10089-368 Each (150µl) Retrieving Restricted
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SPECIFICATIONS

Antigen Symbol KRAS
Antigen Name Kirsten Rat Sarcoma Viral Oncogene
Reactivity Mouse, Human, Rat
Conjugation Unconjugated
Clonality Polyclonal
Antibody Type Primary
Host Rabbit
Isotype IgG
Western Blot Yes
ELISA Yes
ImmunoChemistry Yes
ImmunoPrecipitation Yes
Flow Cytometry Yes
Antigen Synonyms C-K-RAS, NS3, KI-RAS, K-RAS2A, RALD, K-RAS4B, NS, KRAS1, KRAS2, RASK2, K-RAS2B, CFC2, K-RAS4A
Immunogen Recombinant Protein
Purification Antigen affinity Purification
Storage Buffer PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Shipping Temperature Store at -20°C
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