Anti-PSMD14 Rabbit Polyclonal Antibody

Supplier: Proteintech
12059-1-AP-150UL
10092-972EA 459.7 USD
10092-972
Anti-PSMD14 Rabbit Polyclonal Antibody
Antibodies
The PSMD14 (POH1, also known as Rpn11/MPR1/S13/CepP1) protein is a metalloprotease component of the 26S proteasome that specifically cleaves 'Lys-63'-linked polyubiquitin chains. The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. PSMD14 is highly expressed in heart and skeletal muscle. In carcinoma cell lines. down-regulation of PSMD14 by siRNA transfection had a considerable impact on cell viability causing cell arrest in the G0-G1 phase, ultimately leading to senescence.

Western Blot: Human Heart Tissue, 1:200-1:2000; IHC: Human Colon cancer, 1:20-1:200

Type: Primary
Antigen: PSMD14
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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