MPZL2 (myelin protein zero-like 2), also named as EVA (epithelial V-like antigen) or EVA1, is a type 1 transmembrane protein of the myelin P0 protein family, containing an Ig-like V-type (immunoglobulin-like) domain and two potential glycosylation sites. MPZL2 is expressed in thymus epithelium and strongly downregulated by thymocyte developmental progression. Its capacity to mediate cell adhesion through a homophilic interaction and its selective regulation by T cell maturation might imply the participation of EVA in the earliest phases of thymus organogenesis. The gene of MPZL2 maps to chromosome 11q24, and encodes a 215-amino acid protein with a predicted unmodified molecular weight of 24.5 kDa. This antibody can be used to detect endogenous MPZL2, however, the reason for the additional band of 32 kDa is still unknown.
Western Blot:Jurkat Cells, 1:500-1:5000
Type: Primary
Antigen: MPZL2
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat