Anti-VWF Rabbit Polyclonal Antibody

Supplier: Proteintech

Anti-VWF Rabbit Polyclonal Antibody

Anti-VWF Rabbit Polyclonal Antibody

Anti-VWF Rabbit Polyclonal Antibody

Anti-VWF Rabbit Polyclonal Antibody

Anti-VWF Rabbit Polyclonal Antibody

Anti-VWF Rabbit Polyclonal Antibody

11778-1-AP-150UL

10097-058EA 537.7 USD

10097-058

Anti-VWF Rabbit Polyclonal Antibody

Antibodies

Von Willebrand factor (vWF) is a large multimeric glycoprotein that is crucial to the hemostasis process. It supports platelet adhesion and carries factor VIII (FVIII). Deficiency of vWF results in von Willebrand disease (vWD), a common inherited bleeding disorder. The pre-pro-vWF is comprised of 2,813 amino acids (aa) which encompass a 22-aa signal peptide, a 741-aa large propeptide (vWF propeptide, vWFpp, also called von Willebrand antigen II) and 2,050 aa making up the mature vWF. The von Willebrand antigen 2 is required for multimerization of vWF and for its targeting to storage granules. This antibody raised against the N-terminal region (residues 56-256 aa) of pre-pro-vWF recognizes von Willebrand antigen 2 (75-83 kDa) and pro-vWF (309-320 kDa).

Western Blot:Jurkat Cells, 1:200-1:2000; IHC: Human Liver Tissue, 1:20-1:200

Type: Primary
Antigen: VWF
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat

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