Anti-RRM2 Rabbit Polyclonal Antibody

Supplier: Proteintech
10094-004EA 524.48 USD
Anti-RRM2 Rabbit Polyclonal Antibody
Ribonucleotide reductase M2 subunit is one of two subunits that constitute ribonucleotide reductase, the enzyme that catalyzes the conversion of ribonucleotide 5'-diphosphates into 2'-deoxyribonucleotides, a rate-limiting step in the production of 2'-deoxyribonucleoside 5'-diphosphates (dNTP) required for DNA synthesis and repair that is required for DNA synthesis and repair . RRM2 is only expressed during the late G1/early S phase, and degraded in late S phase, and the activity of RNR, and therefore DNA synthesis and cell proliferation, is controlled during the cell cycle by the synthesis and degradation of RRM2 subunit .

Western Blot:K-562 Cells, 1:200-1:2000; IHC: Human tonsillitis Tissue, 1:20-1:200

Type: Primary
Antigen: RRM2
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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