Anti-MALT1 Rabbit Polyclonal Antibody

Supplier: Proteintech
10089-914EA 402 USD
Anti-MALT1 Rabbit Polyclonal Antibody
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 belongs to caspase-like protein superfamily.MALT1 plays a potential role in the regulation of apoptosis and induces NFKB activation and required for the normal development of B cells and for the activation of the IKK complex.It acts as a caspase and mediates additional functions related to T cell activation, cleaving both the ubiquitin editing enzyme,TNFAIP3,and the C terminus of BCL10 .It has two isoforms.Researches showed that inhibition of MALT1 blocks A20 and BCL10 cleavage, reduces NFKB activity, and decreases the expression of NFKB targets BCLXL.

IHC: Human Lymphoma Tissue, 1:20-1:200; IF: HepG2 Cells, 1:10-1:100; Western Blot: HeLa Cells, 1:200-1:2000; FC: HeLa Cells, N/A

Type: Primary
Antigen: MALT1
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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