Anti-PDPN Rabbit Polyclonal Antibody

Supplier: Proteintech
10081-384EA 402 USD
Anti-PDPN Rabbit Polyclonal Antibody
M2A(D2-40) antigen is a previously identified marker for CIS and seminoma. M2A (D2-40) antigen has been identical to PDPN.. PDPN, also named as GP36, Gp38, GP40, HT1A-1, OTS8, PA2.26, T1A and T1A-2, has a function in developing testis, most likely at the level of cell-cell interactions among pre-meiotic germ cells and immature Sertoli cells. It may be involved in cell migration and/or actin cytoskeleton organization. When expressed in keratinocytes, PDPN induces changes in cell morphology with transfected cells showing an elongated shape, numerous membrane protrusions, major reorganization of the actin cytoskeleton, increased motility and decreased cell adhesion. It is required for normal lung cell proliferation and alveolus formation at birth. PDPN induces platelet aggregation. It does not have any effect on folic acid or amino acid transport and does not function as a water channel or as a regulator of aquaporin-type water channels. The antibody is special to PDPN.

IHC: Human Colon cancer Tissue, 1:20-1:200

Type: Primary
Antigen: PDPN
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human
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