TRIP-Br proteins are a set of proteins with the potential to function in both transcriptional control and cell cycle regulation . CECA4 is a member of TRIP-br family, based on its homologous sequence motifs including SERTA and a PHD-bromo-binding site which interacts with a series of bromodomain containing transcriptional cofactors. When activated by E2F, CDCA4 consequently functions as a suppressor of E2F-responsive promoters to participate the regulation of cell proliferation through the E2F/pRb pathway .
Western Blot: HeLa Cells, 1:200-1:2000
Type: Primary
Antigen: CDCA4
Clonality: Polyclonal
Clone: 0
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: