Anti-PUM2 Rabbit Polyclonal Antibody

Supplier: Proteintech
10093-094EA 402 USD
Anti-PUM2 Rabbit Polyclonal Antibody
PUM2 (Human Pumilio homology protein 2), a member of the PUF protein family, binds to 3′ untranslated regions (3′ UTRs) of mRNA and to repress gene expression by controlling cytoplasmic polyadenylation and affecting mRNA translation . When translationally dormant, PUM2, CPEB (CPE-binding protein) and Maskin form a complex on maternal cyclin B1 mRNA, precluding the formation of the active translation initiation complex . PUM2 has been found to play a role in the mammalian nervous system, in particular in regulating morphology, arborization and excitability of neuronal dendrites .

Western Blot: Mouse Testis Tissue, 1:500-1:5000

Type: Primary
Antigen: PUM2
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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