Anti-LIAS Rabbit Polyclonal Antibody

Supplier: Proteintech
11577-1-AP-150UL
10088-228EA 459.7 USD
10088-228
Anti-LIAS Rabbit Polyclonal Antibody
Antibodies
LIAS(lipoyl synthase, mitochondrial) is also named as LAS and belongs to the radical SAM superfamily and lipoyl synthase family. It produces alpha-lipoic acid, an antioxidant and an essential cofactor in alpha-ketoacid dehydrogenase complexes, which participate in glucose oxidation and ATP generation. The deduced 373-amino acid protein has a calculated molecular mass of about 42 kD. The N-terminal 26 amino acids encode a potential mitochondrial targeting presequence that, upon removal, would result in a deduced mature protein of 347 amino acids with a molecular mass of about 39 kD. Defects in LIAS are a cause of pyruvate dehydrogenase lipoic acid synthetase deficiency (PDHLD).

Western Blot: Human Brain Tissue, 1:500-1:5000; IHC: Human Lymphoma Tissue, 1:20-1:200

Type: Primary
Antigen: LIAS
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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