Anti-OGT Rabbit Polyclonal Antibody

Supplier: Proteintech
10091-566EA 537.7 USD
Anti-OGT Rabbit Polyclonal Antibody
O-linked N-acetylglucosamine transferase (OGT) catalyzes the attachment of N-acetylglucosamine (GlcNAc) monosaccharides to the hydroxyl group of serine or threonine residues of numerous nuclear and cytoplasmic proteins and may play important roles in a large number of diverse intracellular processes ranging from translational control, transcription, transcriptional repression, insulin resistance and regulation of the cell cycle. It exists as a heterotrimeric complex with two 110 kDa and one 70 kDa subunits. Recent studies have shown that O-GlcNAcylation plays essential roles in cancer formation and progression. O-GlcNAcylation as well as OGT expression was found to be significantly elevated in the cancer tissues.

Western Blot: Human Brain Tissue, 1:500-1:5000; IHC: Human pancreas cancer Tissue, 1:20-1:200; IP: Mouse Brain Tissue, 1:500-1:5000

Type: Primary
Antigen: OGT
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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