Anti-FUS/TLS Rabbit Polyclonal Antibody

Supplier: Proteintech
11570-1-AP-150UL
10087-186EA 402 USD
10087-186
Anti-FUS/TLS Rabbit Polyclonal Antibody
Antibodies
FUS (also named TLS and POMp75) belongs to the RRM TET family. FUS may play a role in the maintenance of genomic integrity; it binds both single-stranded and double-stranded DNA and promotes ATP-independent annealing of complementary single-stranded DNAs and D-loop formation in superhelical double-stranded DNA. FUS is also an RNA-binding protein, and its links to neurodegenerative disease proffer the intriguing possibility that altered RNA metabolism or RNA processing may underlie or contribute to neuron degeneration. FUS may be a cause of angiomatoid fibrous histiocytoma (AFH) and is implicated in certain forms of amyotrophic lateral sclerosis (ALS) and frontotemporal dementias (FTDs) such as frontotemporal lobar dementia with ubiquitin inclusions (FTLD-U). This antibody is a rabbit polyclonal antibody raised against an internal region of human FUS.

Western Blot: HEK-293 Cells, 1:1000-1:10000; IHC: Human ovary tumor Tissue, 1:20-1:200; IF: HepG2 Cells, 1:10-1:100; IP:K-562 Cells, 1:500-1:5000; FC: HeLa Cells, N/A

Type: Primary
Antigen: FUS/TLS
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
Order Now

Learn more

About VWR

Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...

Learn more About VWR