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Anti-FUS/TLS Rabbit Polyclonal Antibody

Supplier: Proteintech
FUS (also named TLS and POMp75) belongs to the RRM TET family. FUS may play a role in the maintenance of genomic integrity; it binds both single-stranded and double-stranded DNA and promotes ATP-independent annealing of complementary single-stranded DNAs and D-loop formation in superhelical double-stranded DNA. FUS is also an RNA-binding protein, and its links to neurodegenerative disease proffer the intriguing possibility that altered RNA metabolism or RNA processing may underlie or contribute to neuron degeneration. FUS may be a cause of angiomatoid fibrous histiocytoma (AFH) and is implicated in certain forms of amyotrophic lateral sclerosis (ALS) and frontotemporal dementias (FTDs) such as frontotemporal lobar dementia with ubiquitin inclusions (FTLD-U). This antibody is a rabbit polyclonal antibody raised against an internal region of human FUS.

Western Blot: HEK-293 Cells, 1:1000-1:10000; IHC: Human ovary tumor Tissue, 1:20-1:200; IF: HepG2 Cells, 1:10-1:100; IP:K-562 Cells, 1:500-1:5000; FC: HeLa Cells, N/A

Type: Primary
Antigen: FUS/TLS
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat

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Size Supplier No. VWR Catalog Number Unit Price Quantity
150 µL 11570-1-AP 10087-186 Each (150µl) Retrieving Restricted

Temperature sensitive This Item is temperature sensitive and has specific temperature and storage requirements for shipping/delivery. Requires a maximum 2 day delivery.

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Antigen Symbol FUS/TLS
Reactivity Rat, Mouse, Human
Conjugation Unconjugated
Clonality Polyclonal
Antibody Type Primary
Host Rabbit
Isotype IgG
Western Blot Yes
ImmunoChemistry Yes
ImmunoPrecipitation Yes
ImmunoFluorescence Yes
Flow Cytometry Yes
Immunogen Recombinant Protein
Purification Antigen affinity Purification
Storage Buffer PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Shipping Temperature Store at -20°C
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