The SIX proteins (sine oculis) are a family of homeodomain transcription factors that share a conserved DNA binding domain. Six members (Six1-Six6) of the Six gene family have been identified in mice and humans. SIX2, containing one homeobox DNA-binding domain, is highly expressed in fetal tissues but expression is limited in adult tissues. SIX2 may be involved in limb tendon and ligament development. It has been previously shown that SIX2 is expressed in developing mesenchymal tissue including head and urogenital system at the time of overt midfacial and renal differentiation. This antibody is a rabbit polyclonal antibody raised against full length SIX2 of human origin.
Western Blot: HEK-293 Cells, 1:200-1:2000; IHC: Human Kidney Tissue, 1:20-1:200; IF: Mouse Embryonic Kidney, 1:20-1:200; IP: HEK-293 Cells, 1:200-1:2000
Type: Primary
Antigen: SIX2
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat