MCC (mutated in colorectal cancers) gene been previously been identified by virtue of its mutation in human colorectal tumors. As a candidate for the putative colorectal tumor suppressor gene located at 5q21, MCC protein suppresses cell proliferation and the Wnt/b-catenin pathway in colorectal cancer cells. In addition, MCC is involved in cell migration via binding with Srib and b-catenin,
IHC: Human Prostate Cancer Tissue, 1:20-1:200; IP:PC-3 Cells, 1:200-1:2000; Western Blot: Human Brain Tissue, 1:200-1:2000
Type: Primary
Antigen: MCC
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse