Anti-BubR1 Rabbit Polyclonal Antibody

Supplier: Proteintech
10083-732EA 402 USD
Anti-BubR1 Rabbit Polyclonal Antibody
BUB1B(Mitotic checkpoint serine/threonine-protein kinase BUB1 beta) is lalso named as BUBR1, MAD3L, SSK1 and belongs to the BUB1 subfamily. Human BUB1B is a 120 kDa protein that plays a central role in the spindle assembly checkpoint (SAC), the evolutionary conserved and self-regulatory system of higher organisms that monitors and repairs defects in chromosome segregation in mitotic cells. In addition to phosphorylation, BUB1B is also subjected to posttranslational modifications including acetylation. Defects in BUB1B are the cause of premature chromatid separation trait (PCS) and mosaic variegated aneuploidy syndrome type 1 (MVA1).

Western Blot: Mouse Testis Tissue, 1:500-1:5000; IHC: Human Colon cancer Tissue, 1:10-1:100

Type: Primary
Antigen: BubR1
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse
Order Now

Learn more

About VWR

Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...

Learn more About VWR