Anti-FRS2 Rabbit Polyclonal Antibody

Supplier: Proteintech

Anti-FRS2 Rabbit Polyclonal Antibody

Anti-FRS2 Rabbit Polyclonal Antibody

Anti-FRS2 Rabbit Polyclonal Antibody

Anti-FRS2 Rabbit Polyclonal Antibody

Anti-FRS2 Rabbit Polyclonal Antibody

Anti-FRS2 Rabbit Polyclonal Antibody

11503-1-AP-150UL

10087-154EA 402 USD

10087-154

Anti-FRS2 Rabbit Polyclonal Antibody

Antibodies

Fibroblast growth factor (FGF) receptor substrate 2 (FRS2) has an alternative name as SNT-1, it is an adapter protein that links activated FGR and NGF receptors to downstream signaling pathways. FGF receptor substrates (FRS2 and FRS3) are key adaptor proteins that mediate FGF-FGFR signalling in benign as well as malignant tissue. FRS2 is a 508 amino-acid protein,which is phosphorylated on tyrosine residues. The molecular weight of non-phosphorylated FRS2 is 57-68 kDa, but phosphorylated FRS2 is 80-90 kDa. Phosphorylation of FRS2 is associated with activation of a number of MAP kinases. Allele-specific regulation of FGFR2 mRNA expression with a mildly increased breast cancer risk has been reported.

Western Blot: MCF-7 Cells, 1:500-1:5000; IHC: Human Prostate Cancer Tissue, 1:20-1:200

Type: Primary
Antigen: FRS2
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat

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