Anti-SPRY2 Rabbit Polyclonal Antibody

Supplier: Proteintech
10095-126EA 402 USD
Anti-SPRY2 Rabbit Polyclonal Antibody
Sprouty(SPRY) genes encode intracellular inhibitors of receptor tyrosine kinase (RTK) signaling pathways, including those triggered by fibroblast growth factors (Fgfs). In addition to its well-reported function as an inhibitor of the RAS/RAF/MEK signalling cascade, SPRY2 exerts its inhibitory role in the PI3K/AKT signalling pathway throuth PTEN, and inhibits ERK/MAPK activity via EGFR trafficking.

Western Blot: Human duodenum Tissue, 1:200-1:2000; IHC: Human pancreas cancer Tissue, 1:20-1:200; IF:A375 Cells, 1:10-1:100

Type: Primary
Antigen: SPRY2
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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