Anti-BECN1 Rabbit Polyclonal Antibody

Supplier: Proteintech
10082-324EA 402 USD
Anti-BECN1 Rabbit Polyclonal Antibody
Beclin-1 (BECN1), also known as ATG6 or VPS30, has a central role in autophagy, a process of programmed cell survival, which is increased during periods of cell stress and extinguished during the cell cycle. Beclin-1, may play a role in antiviral host defense. It protects against infection by a neurovirulent strain of Sindbis virus. Beclin-1 participates in the regulation of autophagy and has an important role in development, tumorigenesis, and neurodegeneration. A progressively reduced Beclin-1 expression is reported to correlate with the primary tumor growth of squamous cell carcinoma and adenocarcinoma of the lung. Caspase-mediated cleavage of Beclin 1 promotes crosstalk between apoptosis and autophagy.

Western Blot: MDA-MB-453s Cells, 1:500-1:5000; IHC: Human Colon cancer Tissue, 1:20-1:200; IP: HeLa Cells, 1:200-1:2000

Type: Primary
Antigen: BECN1
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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