Anti-CREB3 Rabbit Polyclonal AntibodySupplier: Proteintech
10085-168EA 537.7 USD10085-168
Anti-CREB3 Rabbit Polyclonal Antibody
CREB3, also named as LZIP and Luman, belongs to the bZIP family and ATF subfamily. It is a transcription factors activated upon intramembrane proteolysis (RIP), binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters. CREB3 binds to and requires HCFC1 as a coactivator. The activity and expression are suppressed when the HCFC1-CREB3 complex binds with CREBZF. Participates in LKN-1/CCL15-induced chemotaxis signaling. CREB3 is N-glycosylated and released by proteolysis. So the MW of CREB3 emirate 40kd to 64kd.
Western Blot:PC-3 Cells, 1:200-1:2000; IHC: Human prostate cancer, 1:20-1:200
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