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Anti-DGCR8 Rabbit Polyclonal Antibody

Supplier: Proteintech
DGCR8 is a RNA-binding protein that assists the Rnase III enzyme Drosha in the processing of microRNAs (miRNAs), which regulate the expression of a large number of protein-coding genes. DGCR8, which contains two double-stranded RNA (dsRNA)-binding domains, may be an essential component of the primary miRNAs processing complex, along with Drosha, promoting the processing of primary microRNA to precursor microRNA. It is ubiquitous expressed in human and mouse tissues, and is deleted in DiGeorge syndrome[22323604].This antibody is a rabbit polyclonal antibody raised against residues near the C terminal DGCR8 of human origin. The antibody can recognize isoform1 and isoform2 of DGCR8. (NM_022720.6 (120kDa)& 001190326.1(86kDa), respective )

Western Blot:Jurkat Cells, 1:200-1:2000; IHC: Human breast cancer Tissue, 1:20-1:200; IF:SH-SY5Y Cells, 1:20-1:200; IP: HEK-293 Cells, 1:200-1:2000; FC: HeLa Cells, N/A

Type: Primary
Antigen: DGCR8
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat



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Size Supplier No. VWR Catalog Number Unit Price Quantity
150 µL 10996-1-AP 10085-788 Each (150µl) Retrieving Restricted
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SPECIFICATIONS

Antigen Symbol DGCR8
Antigen Name DGCR8 microprocessor complex subunit
Reactivity Rat, Mouse, Human
Conjugation Unconjugated
Clonality Polyclonal
Antibody Type Primary
Host Rabbit
Isotype IgG
Western Blot Yes
ELISA Yes
ImmunoChemistry Yes
ImmunoPrecipitation Yes
ImmunoFluorescence Yes
Flow Cytometry Yes
Antigen Synonyms Microprocessor complex subunit DGCR8, C22orf12, DGCRK6, pasha, Gy1
Immunogen Recombinant Protein
Purification Antigen affinity Purification
Storage Buffer PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Shipping Temperature Store at -20°C
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