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Anti-SUMO2 + SUMO3 Rabbit Polyclonal Antibody

Supplier: Proteintech
Ubiquitin is most famous for its function in targeting proteins for degradation by the 26S proteasome, ubiquitin needs to be attached to a substrate in chains (polyubiquitylation) before being recognized by proteasome. Similarly, SUMO (small ubiquitin-related modifier) can be linked to substrates in chains (polysumoylation), SUMO modification has been implicated in many important cellular processes including the control of genome stability, signal transduction, targeting to and formation of nuclear compartments, cell cycle and meiosis. There are 4 confirmed SUMO isoforms in human, SUMO-1, SUMO-2, SUMO-3 and SUMO-4. SUMO-2 and SUMO-3 are nearly identical but are distinct from SUMO-1. SUMO2/3 conjugation was recently widely involved in neuroprotective activities. A substitution (M55V) of SUMO4 was strongly associated with the pathogenesis of type 1 diabetes (T1D) involving NF kappa B related mechanisms.

Western Blot: HEK-293 Cells, 1:500-1:5000; IHC: Human Colon cancer, 1:20-1:200

Type: Primary
Antigen: SUMO2 + SUMO3
Clonality: Polyclonal
Conjugation: Unconjugated
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat



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Size Supplier No. VWR Catalog Number Unit Price Quantity
150 µL 10947-1-AP 10082-232 Each (150µl) Retrieving Restricted

Temperature sensitive This Item is temperature-controlled and may have specific temperature and storage requirements for shipping/delivery.

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Antigen Symbol SUMO2 + SUMO3
Antigen Name Small ubiquitin-related modifier 2 And 3
Reactivity Mouse, Human, Rat
Conjugation Unconjugated
Clonality Polyclonal
Antibody Type Primary
Host Rabbit
Isotype IgG
Western Blot Yes
ImmunoChemistry Yes
Antigen Synonyms SMT3 suppressor of mif two 3 homolog 1, ubiquitin-like protein SMT3A, SMT3H1, Smt3B, SUMO-2, SUMO2, SMT3A, SMT3 homolog 1, ubiquitin-like protein SMT3B, small ubiquitin-related modifier 3, SUMO-3, Sumo3
Immunogen Recombinant Protein
Purification Antigen affinity Purification
Storage Buffer PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Shipping Temperature Store at -20°C
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