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Anti-CTCF Rabbit Polyclonal Antibody

Supplier: Proteintech
Transcriptional insulators are DNA elements that set boundaries on the actions of enhancer and silencer elements and thereby organize the eukaryotic genome into regulatory domains. All vertebrate insulators appear to use the versatile CTCF protein. CTCF uses various combinations of its 11 zinc fingers to recognize a variety of unrelated DNA sequences. Once bound to DNA, CTCF can function as a transcriptional insulator, repressor, or activator, depending on the context of the binding site . In vertebrates, this 11 zinc-finger protein is shown to be crucial in processes of epigenetic imprinting, X chromosome inactivation , and associated with various complex human diseases including cancer and diabetes .

Western Blot: Human Brain Tissue, 1:200-1:2000; IHC: Human Lymphoma Tissue, 1:20-1:200; IP: MCF-7 Cells, 1:200-1:1000

Type: Primary
Antigen: CTCF
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype:
Reactivity:



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Size Supplier No. VWR Catalog Number Unit Price Quantity
150 µL 10915-1-AP 10085-300 Each (150µl) Retrieving Restricted
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SPECIFICATIONS

Antigen Symbol CTCF
Antigen Name CCCTC-binding Factor
Reactivity Human, Rat
Conjugation Unconjugated
Clonality Polyclonal
Antibody Type Primary
Host Rabbit
Isotype IgG
Western Blot Yes
ELISA Yes
ImmunoChemistry Yes
ImmunoPrecipitation Yes
Antigen Synonyms 11 zinc finger transcriptional repressor, 11-zinc finger protein, CTCFL paralog, transcriptional repressor CTCF
Immunogen Recombinant Protein
Purification Antigen affinity Purification
Storage Buffer PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Shipping Temperature Store at -20°C
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